Drug design at the atomic level to thwart COVID-19

Ella Castle

Stanford researchers aim to get ahead of coronavirus evolution by designing antiviral drugs that continue to work on Paxlovid-resistant mutants. (Image credit: Getty Images) Although COVID-19 has faded from the headlines, SARS-CoV-2 – the coronavirus behind the pandemic – is still rampantly infecting people around the world. Public health officials […]

COVID-19 Increases Risk for Autoimmune Inflammatory Rheumatic Disease

Ella Castle

Credit: Puwadol Jaturawutthichai/Shutterstock A large study led by Kyung Hee University in Seoul shows that infection with SARS-CoV-2 significantly increases the risk of developing autoimmune inflammatory rheumatic disease for up to a year after infection. The research, published in the Annals of Internal Medicine, shows that COVID-19 increased the risk […]

Research suggests COVID-19 affects brain age and IQ score

Ella Castle

Ziyad Al-Aly is chief of research and development at VA St. Louis Health Care System and a clinical epidemiologist at Washington University in St. Louis. From the very early days of the pandemic, brain fog emerged as a significant health condition that many experience after COVID-19. Brain fog is a colloquial term […]

CDC Shortens COVID-19 Isolation Period

Ella Castle

Key Takeaways The CDC says people with COVID no longer need to isolate for five days. They can leave their homes after being fever-free for 24 hours without the help of medications if symptoms are improving. People with COVID-19 no longer need to isolate for five days before returning to […]

COVID-19 antiviral treatment should be taken for longer, says study

Ella Castle

Viral and spike antibody dynamics in molnupiravir (purple) and Usual Care (gray) arms. a) Median viral load ±95%CI with time, below limit of quantification (BLOQ) measures substituted with LOQ/2 for molnupiravir (n = 253) and Usual Care (n = 324) compared with a Mann–Whitney test. b) Viral load with time showing multivariable linear viral […]

When Covid-19 finally got me, here’s what I did next

Ella Castle

Get inspired by a weekly roundup on living well, made simple. Sign up for CNN’s Life, But Better newsletter for information and tools designed to improve your well-being. Story highlights Getting a Covid-19 vaccination reduces risk of hospitalization or death All should have a plan in the event of infection, our […]

Paxlovid enhances treatment options for COVID-19 patients

Ella Castle

In a recent review published in the Pharmaceutics, a group of authors explored the design, synthesis, and mechanism of action of Paxlovid, a Protease inhibitor (PI) drug combination for treating coronavirus disease 2019 (COVID-19). Study: The Design, Synthesis and Mechanism of Action of Paxlovid, a Protease Inhibitor Drug Combination for the […]

At-Home OTC COVID-19 Diagnostic Tests

Ella Castle

Abbott Diagnostics Scarborough, Inc.:BinaxNOW COVID-19 Ag Card Home Test People with symptoms that began within the last 7 days. The test is to be performed two times over three days (serial testing). People without symptoms. The test is to be performed three times over five days (serial testing). Age 15 […]

5 things to know about Tampa Bay’s COVID-19 spike

Ella Castle

COVID-19 is here to stay, and Tampa Bay is again weathering a winter uptick of the pathogen. While mask mandates and other restrictions are long gone, experts say there are simple ways to protect vulnerable residents. Here are five things to know about COVID-19′s continued spread across the region and […]

Paxlovid treatment in 20% of COVID-19 patients could avert 850,000 hospitalizations, save up to $170 billion

Ella Castle

In a recent study published in the journal Emerging Infectious Diseases, researchers used data from a large case-cohort clinical trial (1,120 cases, 1,126 controls) to simulate 24 separate scenarios wherein the use of the Pfizer-developed antiviral drug ‘Paxlovid’ could benefit the Stated States of America’s (US’s) medical and economic sectors. […]

Antiviral Treatment of Mild-to-Moderate COVID-19

Ella Castle

  Funded through sponsorship by Pfizer Private Limited. Medscape approached Pfizer Private Limited to fund the production of this editorial article. Please see bottom of page for full disclaimer.   Background Although the emergency phase of the coronavirus disease 2019 (COVID-19) pandemic ended in May 2023, the virus is still […]

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