Drug design at the atomic level to thwart COVID-19

Ella Castle

Stanford researchers aim to get ahead of coronavirus evolution by designing antiviral drugs that continue to work on Paxlovid-resistant mutants. (Image credit: Getty Images) Although COVID-19 has faded from the headlines, SARS-CoV-2 – the coronavirus behind the pandemic – is still rampantly infecting people around the world. Public health officials […]

COVID Booster Shots Reshape Immune Memory

Ella Castle

Credit: matejmo/Getty Images T cell populations can change significantly after each COVID mRNA vaccine or booster, a new study from Japan demonstrates. The study, which included about 40 patients and used TCR sequencing, shows certain spike epitopes can become immunodominant. In addition, the team found intra-epitope shifts of vaccine-responding immune […]

A call for better diagnosis and treatment

Ella Castle

In a recent review published in the journal Nature Reviews Microbiology, a group of authors summarized recent advancements in understanding long coronavirus disease (COVID) ‘s mechanisms, impacts, and research needs for better diagnostics and treatments. Review: Long COVID: major findings, mechanisms and recommendations Background Long COVID, affecting over 65 million globally, […]

COVID-19 Increases Risk for Autoimmune Inflammatory Rheumatic Disease

Ella Castle

Credit: Puwadol Jaturawutthichai/Shutterstock A large study led by Kyung Hee University in Seoul shows that infection with SARS-CoV-2 significantly increases the risk of developing autoimmune inflammatory rheumatic disease for up to a year after infection. The research, published in the Annals of Internal Medicine, shows that COVID-19 increased the risk […]

Research suggests COVID-19 affects brain age and IQ score

Ella Castle

Ziyad Al-Aly is chief of research and development at VA St. Louis Health Care System and a clinical epidemiologist at Washington University in St. Louis. From the very early days of the pandemic, brain fog emerged as a significant health condition that many experience after COVID-19. Brain fog is a colloquial term […]

CDC Shortens COVID-19 Isolation Period

Ella Castle

Key Takeaways The CDC says people with COVID no longer need to isolate for five days. They can leave their homes after being fever-free for 24 hours without the help of medications if symptoms are improving. People with COVID-19 no longer need to isolate for five days before returning to […]

COVID-19 antiviral treatment should be taken for longer, says study

Ella Castle

Viral and spike antibody dynamics in molnupiravir (purple) and Usual Care (gray) arms. a) Median viral load ±95%CI with time, below limit of quantification (BLOQ) measures substituted with LOQ/2 for molnupiravir (n = 253) and Usual Care (n = 324) compared with a Mann–Whitney test. b) Viral load with time showing multivariable linear viral […]

COVID explained by healthcare professionals

Ella Castle

AUGUSTA COUNTY – Since the start of the pandemic, over one million Americans have died due to COVID-19. The Center for Disease Control (CDC) public health emergency ended last May, but COVID has not left. The University of Virginia held a press briefing in January with Dr. Costi Sifri, who outlined […]

Long term outcomes of hyperbaric oxygen therapy in post covid condition: longitudinal follow-up of a randomized controlled trial

Ella Castle

In this long-term longitudinal follow-up of the active treatment group in our original randomized controlled trial, we found HBOT effects on quality of life, emotional well-being, sleep quality and neuropsychological symptoms in long COVID patients were maintained even more than 1 year (486 ± 73) after the last HBOT session. In all […]

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